PuriActives® Sodium Algin Sulfate

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[PuriActives® Sodium Algin Sulfate The Marine-Derived GAGs Biomimetic for Ultimate Cellular Regeneration] Company: PuriPharm Co. Ltd. Product Category: Active Ingredient / Anti-Aging & Skin Barrier Repair Format: Technical & Marketing Brochure 1. Executive Summary PuriActives® Sodium Algin Sulfate is an advanced, highly purified sulfated polysaccharide derived from premium marine brown algae. Engineered through precise biomimetic biotechnology, it acts as a structural and functional analogue to endogenous Glycosaminoglycans (GAGs), specifically Heparan Sulfate. By mimicking the extracellular matrix's (ECM) natural biological environment, Sodium Algin Sulfate plays a crucial role in stabilizing growth factors, reducing chronic inflammation ("inflammaging"), and accelerating deep skin tissue repair. It is the ultimate marine-biotech solution for premium anti-aging, soothing, and post-procedure recovery formulations. 2. The Scientific Rationale: A Master of the Extracellular Matrix (ECM) As skin ages, the natural pool of Heparan Sulfate in the ECM depletes, leading to structural collapse, impaired cellular communication, and accelerated wrinkling. PuriActives® Sodium Algin Sulfate features a precisely controlled Degree of Sulfation (DS) that closely mimics human GAGs. Growth Factor Stabilization: Its negatively charged sulfated topology allows it to bind specifically to endogenous growth factors (e.g., FGF, EGF, TGF-β), protecting them from proteolytic degradation and amplifying their signaling pathways for collagen synthesis. MMP Inhibition: It competitively binds to and inhibits Matrix Metalloproteinases (MMPs), particularly Hyaluronidase and Elastase, preserving the skin's natural hyaluronic acid and elastin reservoirs. 3. Core Clinical Efficacies I. Profound Anti-Aging & Wrinkle Reduction By acting as a biological reservoir for growth factors, Sodium Algin Sulfate stimulates fibroblast proliferation and upregulates the synthesis of Collagen I and III. It restores the dermal-epidermal junction (DEJ) architecture, resulting in visibly firmer skin and a reduction in fine lines. II. Rapid Barrier Repair & Soothing Exhibiting exceptional anti-inflammatory properties, it actively downregulates pro-inflammatory cytokines (such as IL-1α and TNF-α). It accelerates epidermal re-epithelialization, making it highly effective for sensitive skin, rosacea, and post-aesthetic procedure care (e.g., post-laser, post-peel). III. Deep, Sustained Hydration Unlike standard humectants that merely hold water on the surface, its high molecular weight and dense charge network create a breathable, 3D bio-polymeric film. This shields against trans-epidermal water loss (TEWL) while actively modulating cellular hydration channels from within. 4. Technical Specifications & Formulation Guidelines INCI Name: Sodium Algin Sulfate (and) Water (Aqua) Appearance: Clear to slightly yellowish, viscous liquid. Odor: Characteristic (mild marine origin). Solubility: 100% soluble in water. Insoluble in oils and high concentrations of ethanol. pH Value (at 20°C): 5.0 – 7.5 Recommended Usage Level: 1.0% – 5.0% Formulation Advantages (The PuriPharm Edge): High Compatibility: Compatible with a wide range of cosmetic chassis, including clear serums, O/W emulsions, and hydrogels. Stability: Highly stable against thermal stress (up to 80°C) and light. Can be added to the aqueous phase before homogenization or post-added during the cooling phase below 40°C. Synergistic Potential: Pairs perfectly with peptides, ceramides, and PuriPharm's NanoActive® encapsulates (like NanoActive® Phloretin) for comprehensive anti-aging and barrier-repair protocols. 5. Application Horizons Intensive Anti-Aging Serums: To restructure the dermal matrix and enhance firmness. Dermatological Soothing Creams: For hypersensitive, reactive, or compromised skin. Post-Procedure Care: Accelerating recovery after laser treatments, micro-needling, or chemical peels. Scalp Care Therapies: Reducing scalp inflammation and maintaining follicular ECM health. PuriPharm Co. Ltd. Active Science. Advanced Delivery. Real Impact. For technical dossiers, material safety data sheets (MSDS), or formulation assistance, please contact our R&D support team. Email: Service@puripharm.com | Web: www.PuriActives.com [PuriActives® 硫酸海藻酸钠 (Sodium Algin Sulfate)] PuriActives® 硫酸海藻酸钠 (Sodium Algin Sulfate) 源自海洋的糖胺聚糖 (GAGs) 仿生替代物，重塑细胞终极再生力 公司： 浦瑞生物医药 (PuriPharm Co. Ltd.) 产品类别： 功效活性原料 / 抗衰老与皮肤屏障修复 文档性质： 核心技术与市场推广说明书 (TDS & Brochure) 1. 核心摘要 (Executive Summary) PuriActives® 硫酸海藻酸钠是一款提取自优质海洋褐藻的尖端、高纯度硫酸化多糖聚合物。我们通过精密的仿生生物技术对其进行工程化重塑，使其在结构和功能上高度模拟人体内源性糖胺聚糖 (GAGs)，尤其是硫酸乙酰肝素 (Heparan Sulfate)。 通过完美模拟细胞外基质 (ECM) 的天然生物微环境，硫酸海藻酸钠在稳定生长因子、阻断慢性炎症（即“炎性衰老” Inflammaging）以及加速深层皮肤组织修复方面发挥着决定性作用。它是专为顶级抗衰老、敏肌舒缓及医美术后修复配方量身定制的终极海洋生物技术解决方案。 2. 科学机制：掌控细胞外基质 (ECM) 的核心架构 伴随肌肤老化，ECM 中天然的硫酸乙酰肝素逐渐枯竭，直接导致真皮层结构塌陷、细胞通讯受损及皱纹的加速生成。 PuriActives® 硫酸海藻酸钠 拥有被精准控制的硫酸基团取代度 (DS)，完美仿生人体天然 GAGs 的立体构象。 生长因子锚定与稳定化 (Growth Factor Stabilization)： 其带负电荷的硫酸化拓扑结构能够与内源性生长因子（如 FGF, EGF, TGF-β）特异性结合，保护这些脆弱的信号蛋白免受蛋白水解酶的降解，并成倍放大它们促进胶原蛋白合成的信号通路。 MMP 靶向抑制 (MMP Inhibition)： 它能竞争性结合并强效抑制基质金属蛋白酶 (MMPs)，特别是透明质酸酶 (Hyaluronidase) 和弹性蛋白酶 (Elastase)，从而从源头守护肌肤天然的玻尿酸与弹性蛋白库。 3. 核心临床功效 (Core Clinical Efficacies) I. 深层抗衰与抚纹重塑 作为生长因子的“生物储水池”，硫酸海藻酸钠能够持续刺激成纤维细胞增殖，上调 I 型和 III 型胶原蛋白的合成。它能有效重建真皮-表皮连接层 (DEJ) 的机械张力网络，显著提升肌肤紧致度，自内而外抚平细纹。 II. 极速屏障修复与舒缓退红 展现出极为卓越的抗炎特性，主动下调促炎细胞因子的表达（如 IL-1α 和 TNF-α）。它能大幅缩短表皮再上皮化进程，对敏感肌、玫瑰痤疮以及光电医美术后（如激光、微针、化学焕肤）的创面愈合具有立竿见影的修护疗效。 III. 深层长效赋水与立体保湿 不同于仅停留在皮肤表面的传统保湿剂，其高分子量与高密度电荷网络能在肌肤表面形成一层透气的 3D 生物聚合物水膜。在强效阻断经表皮水分流失 (TEWL) 的同时，由内而外主动调节细胞液压和水通道，实现真正的深度润泽。 4. 技术规格与配方指南 (Technical Specifications) INCI 名称： 硫酸海藻酸钠 (Sodium Algin Sulfate)、水 (Aqua) 外观： 澄清至微黄色粘稠液体 气味： 极具特征性（微弱的天然海洋来源气息） 溶解性： 100% 水溶；不溶于油脂及高浓度乙醇系统 pH 值 (20°C)： 5.0 – 7.5 推荐添加量： 1.0% – 5.0% 配方优势 (PuriPharm 的技术壁垒)： 卓越的系统兼容性： 与极简透明精华、O/W 乳液、水凝胶及面膜液等各类化妆品底座完美兼容。 极致的理化稳定性： 赋予原料对热应激（最高可耐受 80°C）及光照的极高稳定性。可在均质前加入水相，或在降温至 40°C 以下的冷配阶段添加。 协同增效潜能： 与多肽、神经酰胺以及浦瑞生物的 NanoActive® 纳米包裹体（例如：NanoActive® Phloretin 纳米根皮素）搭配使用，能够构建具有降维打击优势的全维度“抗氧-抗炎-修护”产品矩阵。 5. 市场应用前景 (Application Horizons) 密集抗衰精华： 致力于重塑真皮基质，显著提升面部轮廓紧致度。 皮肤学级舒缓特护霜： 专为高敏、泛红及屏障受损肌肤研发。 医美术后护理 (Post-Procedure)： 缩短激光治疗、微创医美或刷酸后的泛红期与恢复期。 进阶头皮护理疗法： 减少毛囊周围的微炎症（结合根皮素可抑制脂氧合酶活性），维持毛囊 ECM 稳态，赋能防脱固发产品。 浦瑞生物医药技术有限公司 (PuriPharm Co. Ltd.) 源于科学，成于功效 (Active Science. Advanced Delivery. Real Impact.) 索取详细的技术档案数据、MSDS 或配方打样支持，请联系我们的研发与商务支持团队： Email: Service@puripharm.com | Web: www.PuriActives.com Tagged 抗氧化, 抗炎症, 抗过敏.

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상품명

PuriActives® Sodium Algin Sulfate

복합물상품명

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공급사

1곳

제조사

PuriPharm

종류

Actives

용도

Moisturizing, Antioxidant, Acne/Blemish Control

인증·등록

NMPA

구성 성분 (1)

공급사 (1)

규격 및 사용 정보

INCI

Sodium Algin Sulfate (and) Water (Aqua)

CAS 번호

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EC 번호

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원산지

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성상

Clear to slightly yellowish, viscous liquid.

용해성

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pH

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권장 사용량

1.0%–5.0%

보관 조건

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사용 기한

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포장 단위

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기술 문서 (TDS·SDS·COA)

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안전성 자료

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규제 자료

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溶解性

100% 水溶；不溶于油脂及高浓度乙醇系统

Solubility

100% soluble in water. Insoluble in oils and high concentrations of ethanol.

기타 INCI 표기

硫酸海藻酸钠 (Sodium Algin Sulfate)、水 (Aqua)