PuriActives® 7-DHC

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[PuriActives® 7-DHC] Vitamin D3 Precursor for Skin Resilience & Renewal INNOVATION IN SKIN SCIENCE PURIPHARM BRAND ARCHITECTURE 7-DHC: THE RESILIENCE ANCHOR ADDRESSING MODERN SKIN STRESS BEYOND BASIC MOISTURE MARKET DEMAND FOR RESILIENCE WHAT IS 7-DEHYDROCHOLESTEROL? PURIACTIVES® 7-DHC BENEFITS THE BIOLOGICAL PATHWAY CELLULAR STRESS RESILIENCE POST-SUN COMFORT BIOLOGICAL BALANCE & RENEWAL SUBSTANTIATION SUMMARY HSP MRNA UPREGULATION PILOT STUDY RESULTS CLAIM DIRECTION GUIDE TECHNICAL GUIDANCE PRODUCT CONCEPT PROTOTYPES COMPLIANCE & SAFETY THE MARKETING EDGE [PuriActives®7-脱氢胆甾醇(7-DHC)纳米脂质体] 一、产品概述 PuriActives® 7-脱氢胆甾醇（7-DHC）纳米脂质体是由浦瑞生物医药技术有限公司（PuriPharm Co. Ltd.）精心研发的创新护肤成分。7-DHC 是维生素 D3 的前体，在紫外线 B（UVB）照射下可转化为维生素 D3，从而发挥多种生物活性，尤其在皮肤健康和抗老化方面具有巨大潜力。结合公司先进的纳米脂质体技术，该产品能够高效递送 7-DHC 至皮肤细胞，提升其生物利用度，为护肤品带来卓越功效。 二、产品特点 （一）独特的原料优势 ·天然来源：7-DHC 作为维生素 D3 的前体，广泛存在于自然界中，是一种天然的生物活性物质。浦瑞生物医药技术有限公司采用优质的原料来源，确保 7-DHC 的纯度和质量，为护肤品提供安全、可靠的活性成分基础。 ·维生素 D3 前体活性：在皮肤中，7-DHC 可在紫外线 B（UVB）的作用下转化为维生素 D3，进而激活一系列与皮肤健康相关的生物过程。这种转化机制使得 7-DHC 能够根据皮肤的实际需求和光照条件，精准地发挥其生物活性，为皮肤提供个性化的护理。 （二）纳米脂质体技术 ·高效递送：纳米脂质体是一种先进的药物递送系统，能够将 7-DHC 包裹在纳米级别的脂质体结构中。这种结构与皮肤细胞的脂质双层具有高度的亲和性，使得 7-DHC 能够更有效地穿透皮肤屏障，深入皮肤细胞内部，从而提高其生物利用度，确保活性成分能够充分发挥作用。 ·稳定性增强：7-DHC 对光、热、湿度等外部因素较为敏感，容易降解。纳米脂质体能够为 7-DHC 提供一个稳定的微环境，保护其免受外界因素的影响，延长产品的有效期，确保其在护肤品中的稳定性和活性。 ·缓释效果：纳米脂质体具有缓释特性，能够使 7-DHC 在皮肤中缓慢释放，维持较长时间的有效浓度。这种缓释机制有助于持续激活皮肤中的维生素 D3 代谢过程，为皮肤提供持久的护理和保护，减少因瞬间高浓度释放可能引起的皮肤刺激。 三、产品功效 （一）皮肤抗老化 ·抗氧化保护：维生素 D3 及其衍生物具有显著的抗氧化特性，能够中和导致皮肤老化的自由基，减少氧化应激对皮肤细胞的损伤。PuriActives® 7-DHC 纳米脂质体通过激活皮肤中的抗氧化防御机制，如核转录因子红系 2 相关因子 2（Nrf2），增加抗氧化酶的合成，从而有效清除活性氧（ROS），延缓皮肤衰老。 ·促进胶原蛋白生成：维生素 D3 可调节皮肤细胞的增殖和分化，刺激胶原蛋白的合成，同时减少胶原酶的活性，抑制胶原蛋白的降解。PuriActives® 7-DHC 纳米脂质体能够促进皮肤中胶原蛋白和弹性蛋白的生成，增加皮肤的弹性和紧致度，减少皱纹的形成，使皮肤恢复年轻状态。 ·调节细胞信号传导：7-DHC 转化为维生素 D3 后，能够参与皮肤细胞的信号传导过程，调节与衰老相关的基因表达。通过激活抗衰老基因，如 Nrf2，PuriActives® 7-DHC 纳米脂质体有助于维持皮肤细胞的正常生理功能，延缓细胞衰老，提升皮肤的整体健康状况。 （二）光保护 ·紫外线防护：维生素 D3 及其衍生物能够调节皮肤细胞对紫外线的反应，减少紫外线引起的 DNA 损伤和细胞凋亡。PuriActives® 7-DHC 纳米脂质体通过激活皮肤的天然防御机制，增强皮肤对紫外线的耐受性，降低紫外线对皮肤的伤害，减少光老化风险。 ·促进 DNA 修复：在紫外线照射后，维生素 D3 及其衍生物能够促进皮肤细胞的 DNA 修复过程，减少 DNA 损伤的积累。PuriActives® 7-DHC 纳米脂质体能够为皮肤细胞提供必要的修复因子，加速 DNA 修复，降低紫外线引起的皮肤癌风险，为皮肤提供全面的光保护。 （三）皮肤屏障功能改善 ·增强皮肤屏障：维生素 D3 及其衍生物能够调节皮肤屏障功能，促进角质形成细胞的分化和角质层的形成。PuriActives® 7-DHC 纳米脂质体通过激活与皮肤屏障功能相关的信号通路，如芳香烃受体（AhR），增强皮肤屏障的完整性，提高皮肤的保湿能力和抵御外界刺激的能力。 ·调节细胞沟通：7-DHC 转化为维生素 D3 后，能够参与细胞间的沟通和信号传递，促进皮肤细胞之间的协同作用。通过调节细胞沟通，PuriActives® 7-DHC 纳米脂质体有助于维持皮肤细胞的正常生理功能，改善皮肤的整体健康状况，使皮肤更加光滑、细腻。 四、应用场景 PuriActives® 7-脱氢胆甾醇（7-DHC）纳米脂质体适用于多种护肤产品，包括但不限于： ·抗皱精华液：作为核心抗老化成分，能够有效减少皱纹和细纹的出现，提升皮肤的紧致度和弹性。 ·防晒霜：与传统防晒剂协同作用，提供更全面的光保护，减少紫外线对皮肤的伤害，同时促进皮肤的自我修复能力。 ·保湿乳液/面霜：增强皮肤的保湿能力和屏障功能，为皮肤提供持久的滋润和保护，改善皮肤的干燥和粗糙问题。 ·修复面膜：加速皮肤的修复过程，缓解皮肤因外界刺激或紫外线照射引起的损伤，恢复皮肤的健康状态。 ·美白产品：通过调节皮肤中的黑色素生成和分布，减少色素沉着，提亮肤色，使皮肤更加均匀透亮。 五、产品优势 ·高效活性成分：7-DHC 作为维生素 D3 的前体，具有独特的生物活性，能够根据皮肤的实际需求和光照条件，精准地发挥其抗老化、光保护和皮肤屏障功能改善等功效。 ·先进的纳米脂质体技术：纳米脂质体能够高效递送 7-DHC 至皮肤细胞，增强其稳定性和生物利用度，同时具有缓释效果，为皮肤提供持久的护理和保护。 ·天然来源，安全性高：7-DHC 来源于天然原料，经过严格的质量控制和检测，确保产品的安全性和可靠性，适用于各种肤质，包括敏感肌肤。 ·多功能性：PuriActives® 7-DHC 纳米脂质体不仅具有抗老化和光保护的功效，还能够改善皮肤屏障功能，调节细胞信号传导，为护肤品提供多种功能，满足不同消费者的需求。 六、使用建议 ·建议添加量：根据具体的产品配方和功效需求，建议在护肤产品中的添加量为 0.5% – 2.0%。 ·使用方法：在产品配方中，将 PuriActives® 7-DHC 纳米脂质体与其他成分混合均匀，确保其充分分散。 ·注意事项：虽然 7-DHC 来源于天然原料，但仍建议在使用前进行皮肤测试，以确保产品适合个人肤质。如有任何不适或过敏反应，请立即停止使用并咨询专业医生。 七、包装与储存 ·包装：采用密封的玻璃瓶或塑料瓶包装，确保产品的稳定性和安全性。 ·储存条件：建议在阴凉、干燥、避光的环境中储存，避免高温和潮湿，以延长产品的有效期。 PuriActives® 7-脱氢胆甾醇（7-DHC）纳米脂质体凭借其独特的原料优势、先进的纳米脂质体技术和卓越的产品功效，为护肤品市场带来了一种全新的抗老化和光保护解决方案。浦瑞生物医药技术有限公司（PuriPharm Co. Ltd.）专注于天然活性成分研发与纳米递送系统创新，拥有多项专利技术，致力于通过创新技术，为消费者提供高品质、安全可靠的产品，助力皮肤健康和美丽。 免责声明 本宣传册中的技术产品信息，据我们所知是真实准确的。任何意见或建议均不包含任何明示或暗示的保证或担保。购买者在根据浦瑞生物医药技术有限公司代表提供的信息采取行动时承担所有风险。 浦瑞生物医药技术有限公司信息 地址：浙江省湖州市红丰路1366号 电话： 0572-2745768 邮箱：sales@puripharm.com 网址：www.puriactives.com [Product Data Sheet PuriActives®7-DHC Elevate the Skin's Natural Defense] Intended Use PuriActives®7-DHC is a high-purity active ingredient designed for advanced cosmetic and personal care formulations. As the natural precursor to vitamin D3, this innovative ingredient harnesses the skin's inherent photoprotective mechanisms to enhance barrier function and support overall skin health. The product is specifically developed for premium skincare applications where scientifically-backed efficacy and exceptional quality are paramount. 7-Dehydrocholesterol is naturally present in human skin and plays a crucial role in the photoproduction of vitamin D3 upon exposure to UVB radiation. By supplementing the skin's natural reservoir of this essential sterol, PuriActives®7-DHC helps optimize the skin's response to environmental stressors while supporting its natural regenerative processes. Benefits at a Glance Enhances skin barrier function and integrity through natural lipid replenishment Supports the skin's natural photoprotective mechanisms and UV defense response Promotes skin hydration and moisture retention for improved skin comfort Precursor to vitamin D3, supporting skin's natural vitamin D synthesis pathway High purity grade suitable for premium cosmetic formulations Compatible with a wide range of cosmetic formulations and delivery systems INCI (PCPC Name) Properties Physical and Chemical Properties Crystalline solid at room temperature with characteristic sterol structure Lipophilic nature enables excellent skin penetration and bioavailability Stable under recommended storage conditions with proper protection from light Compatible with oil-based and emulsion formulations Applications PuriActives®7-DHC is suitable for a wide range of cosmetic and personal care applications: Premium anti-aging creams and serums targeting skin barrier enhancement Photoprotection and after-sun care products supporting natural skin defense Moisturizing formulations for dry and compromised skin conditions Barrier repair creams and sensitive skin formulations Premium body lotions and skin conditioning products Lip care products and protective balms Recommended Usage Concentration The optimal concentration depends on the specific formulation type, desired efficacy, and target consumer needs. We recommend conducting compatibility and stability testing for each specific formulation. For new product development, starting with 0.5% is suggested for most applications. Formulation Guidelines PuriActives®7-DHC should be incorporated into the oil phase of emulsions during the manufacturing process. The ingredient dissolves readily in warm oils (60-80°C) and can be added to the oil phase before emulsification. For anhydrous formulations, dissolve the ingredient in the oil base with gentle heating. Avoid prolonged exposure to high temperatures and protect from light during processing. Handling Precautions Avoid formation of dust during handling; use appropriate dust control measures Use in well-ventilated areas or under local exhaust ventilation Wear appropriate personal protective equipment (gloves, safety glasses) Avoid contact with eyes, skin, and clothing; wash thoroughly after handling Do not eat, drink, or smoke while handling this product Storage and Handling Store in original containers in a cool, dry, well-ventilated area. Protect from light and moisture. Keep away from heat sources and open flames. Ensure containers are properly sealed after each use to maintain product quality and prevent contamination. Scientific Findings 7-Dehydrocholesterol is a naturally occurring sterol that serves as the immediate precursor to vitamin D3 (cholecalciferol) in the human body. Scientific research has demonstrated several key findings regarding its role in skin health and function: 7-Dehydrocholesterol is present in the epidermis and is converted to previtamin D3 upon exposure to UVB radiation (290-320 nm), which then thermally isomerizes to vitamin D3 As a component of the skin's lipid matrix, it contributes to the structural integrity and barrier function of the stratum corneum Studies suggest that topical application of 7-dehydrocholesterol may help support the skin's natural photoprotective response mechanisms The molecule's lipophilic nature enables effective penetration through the stratum corneum, supporting its bioavailability in skin tissues Research indicates potential benefits for skin barrier enhancement and moisture retention through lipid replenishment Specifications Safety Information PuriActives®7-DHC is not classified as hazardous according to Regulation (EC) No 1272/2008 (CLP). The substance has a favorable safety profile based on available toxicological dataand its natural occurrence in human skin. However, standard laboratory and manufacturing safety practices should be followed when handling this product. For detailed safety information, please refer to the Safety Data Sheet (SDS) available upon request. The product is intended for cosmetic use only and should not be used in pharmaceutical or food applications without appropriate regulatory approval. Regulatory Status Packaging Contact Information DISCLAIMER The information provided in this Product Data Sheet is based on our present knowledge and experience. It is intended to provide general guidance on the use of our product and does not constitute a warranty or guarantee of any specific results. Users should conduct their own tests to determine the suitability of the product for their intended applications. PuriPharm Co. Ltd. assumes no liability for any results obtained through the use of this product. The information contained herein is subject to change without notice. For the most current information, please contact our technical service department. PuriPharm Co. Ltd. | PuriActives®7-DHC | February 2026 Tagged 减少皱纹, 嫩肤, 抗炎症.

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상품명

PuriActives® 7-DHC

복합물상품명

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1곳

제조사

Puripahrm

종류

Actives

용도

Anti-aging/Wrinkle Care, Skin Regeneration

인증·등록

NMPA

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공급사 (1)

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INCI

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성상

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용해성

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pH

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권장 사용량

0.5%–2.0%

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