Skincare for wrinkles

The ingredients with clinical evidence for wrinkles are Retinol(A), Ascorbic Acid(B), Palmitoyl Pentapeptide-4(B), Retinal(B), Adenosine(B-), Lactic Acid(B-). The products below carry them near the front of the label (roughly above 1%), ordered by evidence grade and label position.

Evidence-backed ingredients

Evidence-backed ingredients	Evidence	Studied at	Products
Retinol · avoid in pregnancy	A	0.1–1%	323
Ascorbic Acid	B	10–20%	899
Palmitoyl Pentapeptide-4	B	제품 처방	806
Retinal · avoid in pregnancy	B	0.05–0.1%	118
Adenosine	B-	0.04% (식약처 주름 기능성)	3,820
Lactic Acid	B-	5–10%	759

40 products with these ingredients near the front

All 40 products

By ingredients studied for your concern

FAQ

Which ingredients help wrinkles?

How is this list ordered?

Grades come from the ingredient studies themselves, checked down to the papers; an ingredient listed past the 1% line counts for less. This is an order of ingredient evidence and label position, not a promise that a product works, and no brand pays to move up.

How much Retinol does a product need?

Studies that saw an effect used Retinol at 0.1–1%. Where a label prints no amount, each product page estimates the chance it holds that much from its label position.