Phenol, 2,4-bis(1,1-dimethylethyl)-, phosphite (3:1) is an alkylbenzene.
Definition
US FDA substance register · UNII 834E5H0LFF · registered name TRIS(2,4-DI-TERT-BUTYLPHENYL)PHOSPHITE · single chemical substance
Phenol, 2,4-bis(1,1-dimethylethyl)-, phosphite (3:1) is an alkylbenzene.
Source: PubChem
Tris(Di-t-Butylphenyl) Phosphite is the organic compound that conforms to the formula
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 31570-04-4
- EC No.EU chemical inventory number
- 250-709-6
- DTXSIDUS EPA chemical ID
- DTXSID2027969
- DTXCIDUS EPA compound ID
- DTXCID907969
- IUPAC
- Tris(2,4-di-tert-butylphenyl) phosphite
- Molecular formula
- C42H63O3P
- Molecular weight
- 646.937 g/mol
Measured properties
- Appearance
- Dry Powder, Other Solid, Liquid, Large Crystals, CBI · solid
- Colour
- white
- Melting/freezing point
- 183~186 ℃
- Flash point
- &, gt, 150 ℃
- Vapour pressure
- 0.00013 ㎩
- Water solubility
- (&, lt, 0.09 mg/l at 20 ℃)
- Vapour density
- 22.3
- Relative density
- 1.03
- n-Octanol/water partition coefficient (Kow)
- (&, gt, 6 , calc.)
- Molecular weight
- 646.93
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 101 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant57
- Processing aids not otherwise specified13
- Stabilizing agent7
- Filler5
- UV stabilizer4
- pH regulating agent3
- Fragrance3
- Heat stabilizer3
4 other uses
- Reducing agent2
- Surface modifier2
- Flame retardant1
- Pigment1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to other guideline: "Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics" (1959), the US Association of Food and Drug Officials (AFDO). according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: "Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics" (1959) , the US Association of Food and Drug Officials (AFDO). according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Linked databases 13
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English