Ingredient Dictionary

TETRAHYDROFURFURYL METHACRYLATE

Tetrahydrofurfuryl methacrylate is a member of oxolanes.

Definition

Tetrahydrofurfuryl methacrylate is a member of oxolanes.

US FDA substance register · UNII 120GN9C472 · registered name TETRAHYDROFURFURYL METHACRYLATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Tetrahydrofurfuryl Methacrylate is the heterocyclic compound that conforms to the formula:

Cosmetic roles

Leaves a thin film where appliedFILM FORMING

Safety & regulatory references

Banned: International fragrance standard (IFRA)

Source: IFRA fragrance standards

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Methacrylate Ester Monomers

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name メタクリル酸テトラヒドロフルフリル: 本品は、次の化学式で表される複素環式化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

TETRAHYDROFURFURYL METHACRYLATEINCI테트라하이드로퍼퓨릴메타크릴레이트Korean label name (MFDS standard)2-Propenoic acid, 2-methyl-, (tetrahydro-2-furanyl)methyl esterSynonymメタクリル酸テトラヒドロフルフリルJapanese labelling name

CAS No.chemical registry number: 2455-24-5
EC No.EU chemical inventory number: 219-529-5
DTXSIDUS EPA chemical ID: DTXSID0022191
DTXCIDUS EPA compound ID: DTXCID502191

IUPAC: (Oxolan-2-yl)methyl 2-methylprop-2-enoate
Molecular formula: C9H14O3
Molecular weight: 170.208 g/mol

Measured properties

Appearance: Liquid · Colorless or yellow liquid, [MSDSonline]
Boiling point: 59-62 °C at 0.080 kPa (0.6 mm Hg)
Stability: ... Readily polymerized and easily cross-linked by exposure to heat, peroxide catalysts or UV radiation.
Initial boiling point and range: 59~62 ℃ (at 0.6 mmHg)
Flash point: 96 ℃
Vapour pressure: 0.161 ㎜Hg (at 25℃ (est.))
Relative density: 1.04
n-Octanol/water partition coefficient (Kow): 1.80 ((est.))
Molecular weight: 170.21

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Intermediate2
Film former1
Photosensitive agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

SkinSens1
Skin Sensitization · QSAR Predicted
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, druge and cosmetics, by the Staft of the Division of Pharmacology, US FDA, skin toxicity according to Draize (1959) according to other guideline: US FHSA Federal regulation: 16 CFR 1500.41 equivalent or similar to
Sh
Skin Sensitization · Authoritative
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, druge and cosmetics, by the Staft of the Division of Pharmacology, US FDA, Bewertung von Augen-Lasionen nach Draize (1959) according to other guideline: US FHSA Federal regulation: 16 CFR 1500.42 equivalent or similar to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to