- 피부를 수축시켜 조여 주는 느낌을 줌
- 외부 자극으로부터 피부를 보호함
- 땀 분비를 줄임
- 산소와 반응해 제품이 상하는 것을 늦춤
- 색을 냄
정의
미국 FDA 물질 등록 · UNII 6YRL8BWD9H · 등록명 NEOSAXITOXIN · 단일 화학물질
다른 언어 정의 2개
Neosaxitoxin is a pyrrolopurine that is saxitoxin carrying a hydroxy substituent on the nitrogen atom at position 5. It is a sodium channel blocker that is undergoing clinical trials as a prolonged-duration local anesthetic. It has a role as a toxin, a local anaesthetic, a voltage-gated sodium channel blocker, a neurotoxin, an anti-inflammatory agent, a marine metabolite and a cyanotoxin. It is a pyrrolopurine, a paralytic shellfish toxin, an alkaloid, a carbamate ester, a member of guanidines, a member of hydroxylamines and a ketone hydrate. It is functionally related to a saxitoxin.
출처: PubChem
Neosaxitoxin is a neurotoxin isolated from algae cyanobacteria cells. It conforms to the formula
화장품에서 하는 역할
자세한 자료 — 표시명·식별번호·물성·시험 기록·문헌
별칭·식별 정보
- CAS No.화학물질 등록번호
- 64296-20-4
- EC No.EU 화학물질 목록번호
- 809-831-0
- DTXSID미국 환경청(EPA) 화학물질 번호
- DTXSID70880098
- DTXCID미국 환경청(EPA) 화합물 번호
- DTXCID401529215
- IUPAC
- [(3aS,4R,10aS)-2-Amino-5,10,10-trihydroxy-6-imino-3a,4,5,6,9,10-hexahydro-1H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
- 분자식
- C10H17N7O5
- 분자량
- 315.29 g/mol
제품이 실제로 쓴 용도
미국 EPA에 이 성분을 신고한 제품 5건의 용도입니다. 화장품 밖의 제품도 포함되어 있어, 위쪽 몇 줄이 이 성분의 주된 쓰임으로 읽힌다는 뜻입니다.
- 수렴제1
- 산화 방지1
- 발한 억제1
- 염료1
- 보습제1
출처: 미국 EPA CompTox
관련 문헌
- Site-1 Sodium Channel Blockers as Local Anesthetics: Will Neosaxitoxin Supplant the Need for Continuous Nerve Blocks? · 2015
- Neosaxitoxin, a Long-Lasting Local Anesthetic and its Potential Clinical Applications in Horses · 2023
- Faculty Opinions recommendation of A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia. · 2017
- A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia · 2015
- Neosaxitoxin as a Local Anesthetic: Preliminary Observations from a First Human Trial · 2007