Are PDRN cosmetics and Rejuran treatments the same thing?
As more cosmetics containing “PDRN” have become available, many people expect them to have the same effects as dermatological treatments. Although the names are similar, the delivery methods and purposes are different.
Comparison
- Delivery method
- Dermatological treatment
- Applied to the skin's surface
- Purpose
- Dermatological treatment
- Moisturizing and managing skin condition
- Caution
- Dermatological treatment
- Claims about efficacy must stay within the scope of cosmetics
| Cosmetics | Dermatological treatment |
|---|---|
| Delivery method | Applied to the skin's surface |
| Purpose | Moisturizing and managing skin condition |
| Caution | Claims about efficacy must stay within the scope of cosmetics |
Names found in the full ingredient list of cosmetics
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The key point is that even if ingredient names are similar, the way they are delivered to the skin is different. PDRN refers to ingredients in the polydeoxyribonucleotide family, and in cosmetics it is often included as a moisturizing or conditioning ingredient. Topical products are applied to the skin’s surface; they do not deliver ingredients in the same way as injections.
Rejuran is often mentioned alongside PDRN, but more precisely, it is a medical treatment brand that uses PN (polynucleotide). Since it is injected into the skin, its concentration, formulation, delivery route, and purpose differ from those of cosmetics, and it is difficult to expect the treatment’s effects based only on a cosmetic product’s feel or ingredient list. It’s best to consult a dermatologist about whether to undergo the treatment, taking your skin condition and the possibility of side effects into account.
It’s more realistic to view cosmetics as a supplemental option for addressing dryness or improving how your skin feels. PDRN content and the way ingredients are listed can also vary by product, so check the full ingredient list and directions for use.