Definition
US FDA substance register · UNII 5LIV96LADQ · registered name 2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- South Korea
- Restricted
- Taiwan · United Kingdom
Source: MFDS (Korea) cosmetic regulatory information · ASEAN Cosmetic Directive · EU Cosmetics Regulation · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)
ASEAN
- Field of application and/or use : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Maximum authorised concentration in the finished cosmetic product : (b) 3.0 %
- Other limitations and requirements : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5 % For (a) and (b): • Do not use with nitrosating systems • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers The free base and salts of this hair colouring ingredient, unless prohibited under Annex II, are permitted for use. The direction for use “wear suitable gloves” must be included in label or leaflet text
- Conditions of use and warning which must be printed on the labels : (a)The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows
European Union
- Product Type, body parts : a) Hair dye substance in oxidative hair dye product b) Hair dye substance in non-oxidative hair dye product
- Maximum concentration in ready for use preparation : (b) 3,0 %
- Other : a) Afther mixing oxidative conditions the maximum concentration applied to hair must not exceed 1,5% (a) and (b) - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
- Wording of conditions of use and warnings : Can cause allergic reaction
Source: MFDS (Korea) cosmetic regulatory information
EU Cosmetics Regulation, Annex III (restricted substances), entry 201 · maximum concentration 3.0% · applies to a) Hair dye substance in oxidative hair dye product b) Hair dye substance in non-oxidative hair dye product
EU Cosmetics Regulation, Annex III (restricted substances), entry 251 · maximum concentration (a) 3.0% (b) 3.0% · applies to (a) Oxidising colouring agents for hair dyeing (b) Non-oxidising colouring agents for hair dyeing
Restriction III/201 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 131657-78-8
- EC No.EU chemical inventory number
- 411-440-1
- DTXSIDUS EPA chemical ID
- DTXSID00157169
- DTXCIDUS EPA compound ID
- DTXCID7079660
- IUPAC
- 2-Chloro-6-(ethylamino)-4-nitrophenol
- Molecular formula
- C8H9ClN2O3
- Molecular weight
- 216.62 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- Skin Sens. 1
Skin Sensitization · Authoritative
Source: US EPA CompTox dashboard
Linked databases 17
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU restricted substances (Annex III) 2
- EU SCCS safety opinions
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic regulatory information 2 3 4
- Taiwan FDA cosmetic ingredients
- Taiwan FDA cosmetic regulations
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata