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[NanoActive RES] Nanoactive Res is a novel resveratrol nanoliposome preparation (NanoLiposomal Resveratrol). Product Name: Nano Liposomal Res, Nanoactive Res; BioActive Resveratrol; NanoActive Resveratrol CAS: 501-36-0 Description: Resveratrol (“Res”) is a non-flavonoid polyphenolic compound. A Japanese called Tokaoka was the first one who obtained it by separating it from the roots of Veratrum granginorumin 1940. With the in-depth study of resveratrol, it has been shown that resveratrol has a wide range of activities such as anti-cancer, anti-oxidation, anti-bacteria and anti-inflammation which can be broadly used in medicine, health care products, food, cosmetics and other fields. Resveratrol has many targets in the skin, so it can be used as a skincare product to produce whitening, anti-wrinkle, anti-bacteria, anti-inflammation, acne curing and anti-aging effects. It is an emerging natural active substance with high efficiency. However, resveratrol is hardly soluble in water while easy to be oxidized and discolored, which limits its application in cosmetics. The nano actives, developed with the nano-transmission system (NDS), has a particle size of less than 30nm, and enables the resveratrol to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. This overcomes the original defects while maintaining the advantages with a more convenient and wider range of uses. Resveratrol Number of  papers on resveratrol in PUBMED over years Resveratrol can effectively prolong life span Skincare effect Resveratrol is a natural antioxidant present in plants. Its antioxidant capacity is 20-50 times that of L-C. If applied simultaneously with L-C, the effect will be multiplied. Resveratrol inhibits collagenase, reduces collagen degradation, promotes collagen proliferation, and firms skin. Resveratrol allows cells to enhance their self-defense enzymes, thereby repairing damaged DNA, while effectively inhibiting oncogenic proteins produced by UVB exposure. Resveratrol can effectively inhibit melanin synthesis by reacting with multiple targets required for melanin synthesis, thereby achieving whitening and brightening effect. Resveratrol inhibits melanin synthesis through multiple targets Features NanoActive RES uses FDA GRAS grade materials for high safety NanoActive RES is stable to heat, pH and shearing, so it is convenient to use. NanoActive RES greatly improves the stability and bioavailability of resveratrol NanoActive RES can improve the stability of other active matters in the product and facilitate absorption NanoActive RES is 100% water soluble and 100% oil soluble (amphiphilic), allowing a wide range of uses. Applications Promote collagen synthesis, improve skin thickness and elasticity, remove wrinkles, and firm your skin Inhibit melanin synthesis, reduce pigmentation and whiten your skin Eliminate free radicals and confront skin aging Promote wound healing and reduce scars Anti-bacteria, diminish inflammation and sensitization, and provide analgesic effects Prevent scarring and fibrosis Use:Add it at room temperature. You may heat it to over 40℃ to speed up the dissolution. Recommended dosage: 1-5%. The optimum pH range of the system is 3.0-6.5, and the finished product should be protected from direct exposure to sunlight (using opaque packaging). It is recommended to add UV absorber to day care products. Storage: Keep it away from light at a temperature below 25℃. Experimental proof Resveratrol inhibits intracellular melanin synthesis Resveratrol tyrosinase activity is superior to kojic acid Low concentration of resveratrol (0.001%) can reduce B16F10 cell melanin by 50% Two-week application can provide noticeable whitening effect Resveratrol has obvious anti-wrinkle effect Resveratrol (0.001%) is effective in treating acne [纳米白藜芦醇 Nanoactive Res] 纳米白藜芦醇（Nanoactive Res）是一种新型的白藜芦醇纳米脂质体制剂（NanoLiposomal Resveratrol）。良好的抗氧化，清除自由基性能——白藜芦醇是存在于植物中的天然抗氧化剂；显著美白肌肤有效的解决方案，两周内可见效果，削弱黑色素合成的关键步骤；抗氧化能力为左旋维生素C的20-50倍，与维生素C复配，效果更优。 白藜芦醇(Resveratrol，简称Res)又称芪三酚，是非黄酮类的多酚类化合物。白藜芦醇对皮肤具有令人难以置信的保护作用，当局部应用时，白藜芦醇可降低日晒伤害，改善胶原蛋白的合成和减少细胞损伤，是一种稳定，有效的抗氧化剂。赋予肌肤细胞强效保护，帮助抵御环境的伤害，给予受损细胞更长的自我修复周期。具有很强的氧自由基清除能力。同时具备优异的抗衰老能力，抗脂质过氧化。可以激活与生命相关的多种转录因子相关的STRT1酶活性，延长细胞生命周期。它是一个强有力的清道夫，帮助皮肤细胞免受自由基的有害影响，此外,它是一种很好的抗炎成分。 但是其溶解性差及体内生物利用度低。通常在使用30到60分钟内，白藜芦醇就会被代谢掉。大大削弱了它的功效。易变色这一特性也使配方难度大大提高。 目前市面上使用白藜芦醇有以下几种方式，1.使用稳定的衍生物或化合物：例如甲基化白藜芦醇、乙酰化白藜芦醇、4-羟基白藜芦醇甲基化物、白藜芦醇乙酰阿魏酸酯等；2.使用包裹技术；3.特定工艺，例如纳米乳化技术。 怎么样可以“稳”（提高稳定性）中求“胜”（优化白藜芦醇的使用效果）呢？ 降服“白藜芦醇”，我们有纳米包裹技术！ 利用纳米传输系统（NDS）开发的粒径小于30nm的纳米活性物，让白藜芦醇稳定地包裹于纳米载体之中，能大幅增加吸收效率和生物利用度，很好克服了原有缺陷并保持优点，应用更加便利和广泛。 白藜芦醇 历年来PUBMED上白藜芦醇论文数量 白藜芦醇可以有效延长生物寿命 功效 白藜芦醇是存在于植物中的天然抗氧化剂，抗氧化能力为左旋C的20-50倍，如能与左旋C同时使用，效果加乘。白藜芦醇可以抑制胶原蛋白酶，减少胶原蛋白的降解，促进胶原蛋白增生，紧实。白藜芦醇可以使得细胞增强自我防卫的酶，进而修补破损的DNA，同时有效的抑制由于UVB紫外线照射而产生的致癌蛋白。 白藜芦醇通过多靶标作用抑制黑色素合成 产品特点 NanoActive 白藜芦醇采用FDA GRAS级原料，安全性高 NanoActive 白藜芦醇对热、pH和剪切稳定性好，使用方便 NanoActive 白藜芦醇大大提高了白藜芦醇的稳定性和生物利用度 NanoActive 白藜芦醇能提高产品中其他活性物的稳定性并促进吸收 NanoActive 白藜芦醇可100% 水溶亦100%油溶（两亲性），适用范围广 产品应用 促进胶原蛋白合成 抗菌消炎，消敏镇痛 产品使用：室温下加入，加热至40℃以上可以加快溶解速度，推荐用量：1-5%。体系最佳pH范围3.0-6.5,成品应避免阳光直射（使用不透明包装） 产品储存：25℃以下避光保存。 实验证明 白藜芦醇酪氨酸酶活性效率优于曲酸 中文名称：纳米脂质体白藜芦醇；纳米白藜芦醇；纳米包裹白藜芦醇；水溶性；不变色白藜芦醇；纳米包裹白藜芦醇化妆品原料 Product Name：Nano Liposomal Res，Nanoactive Res;BioActive Resveratrol; NanoActive Resveratrol CAS:501-36-0 Tagged 减少痘印, 抗菌消炎, 抗衰老, 祛痘, 祛皱紧肤, 美白.

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상품명

NanoActive™ Res(리포좀 레스베라트롤)

복합물상품명

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1곳

제조사

PuriPharm

종류

Actives

용도

Antioxidant, Anti-aging/Wrinkle Care

인증·등록

NMPA

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INCI

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CAS 번호

501-36-0

EC 번호

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성상

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용해성

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pH

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권장 사용량

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기술 문서 (TDS·SDS·COA)

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안전성 자료

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Storage

Keep it away from light at a temperature below 25℃.