sh-Polypeptide-155 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene which is a synthesized copy of the human gene that codes for Hyaluronan and Proteoglycan Link Protein 1 is used as such or adapted to the production host. It contains a maximum of 354 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.