sh-Oligopeptide-80 is a single chain synthetic human peptide, produced by fermentation in E. coli and contains 17 amino acids. The starting gene is a synthesized copy of the human gene which codes for Osteocalcin used as such or adapted to the production host. Osteocalcin contains a maximum of 100 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.