s-Frog Pentapeptide-1 (Cyclo Octenyl Tripeptide-111) s-Frog Pentapeptide-2 is the synthetic peptide consisting of s-Frog Pentapeptide-1 and s-Frog Pentapeptide-2 in which the two peptide chains are linked by Cyclo Octenyl Tripeptide-111.