Polygonum Cuspidatum Root Extracellular Vesicles are the extracellular vesicles released into and isolated from the growth media removed from cell cultures of the roots of Polygonum cuspidatum. The accepted scientific name for Polygonum cuspidatum is Fallopia japonica. For further information about botanical nomenclature, consult the section on Botanicals in "Regulatory and Ingredient Use Information."