Methionyl sh-Polypeptide-3 is a single chain synthetic peptide, produced by fermentation in E. coli. The starting gene is synthesized by the addition of the initiation codon for methionine with the gene from sh-Polypeptide-3. The peptide contains 164 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.