CERAMIDE 4
Definition
Ceramide 4 (Retired) is the N-acylated sphingolipid having the erythro structure that conforms generally to the formula, where m has a value ranging from 13 to 27 in which the acyl moiety may be saturated or mono-unsataurated and n has a value ranging from 10 to 16. Ceramide 4 is similar to Ceramide 5, however, the acylating hydroxy acids are generally shorter in Ceramide 4 than in Ceramide 5. The INCI Name, Ceramide 4, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 4 will be retained in the retired monograph, and also published with the new name assignment, Ceramide AS.
Names & identifiers
Cosmetic roles
Safety & regulatory references
Reviewed by CIR: Safety Assessment of Ceramides as Used in Cosmetics
Related literature
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- Synthesis and Absolute Configuration of 6‐Hydroxylated New Ceramides in Human Skin, Ceramides B, 4, 7 and 8 · 2005
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