아스타잔틴
ASTAXANTHIN
定義
이 원료는 다음의 구조를 갖는 유기화합물이다.
식약처 원료 정의: 이 원료는 다음의 구조를 갖는 유기화합물이다.
公式表示名・定義
JCIA 표시명 アスタキサンチン: 本品は、次の化学式で表されるカロチノイド系色素である。
別名・識別情報
- cas
- 472-61-7
- ec
- 207-451-4
- dtxsid
- DTXSID00893777
- dtxcid
- DTXCID101323822
- IUPAC
- (3S,3'S)-3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione
- 분자식
- C40H52O4
- 분자량
- 596.852 g/mol
化粧品での役割
安全性・規制情報
Other restriction: ban substances that deplete the ozone layer
連携済み公式原本データ
注意が必要な場合があります
일반적으로 안전하지만, 드물게 피부 자극을 유발할 수 있으니 사용 전 주의가 필요합니다. Astaxanthin is generally safe and well-tolerated for topical use, suitable for sensitive skin due to its antioxidant and anti-inflammatory effects. Stability and formulation play key roles in its effectiveness and minimizing irritation. It is effective both as a topical and oral antioxidant.
使用の参考
항산화, 피부탄력, 미백, 피부진정, 보습 Astaxanthin is a xanthophyll carotenoid found in natural sources like algae, shrimp, and salmon. It activates key cellular pathways such as Nrf2/ARE, increasing the expression of antioxidant enzymes like superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) that protect skin cells from oxidative stress. Astaxanthin inhibits NF-κB signaling to reduce inflammation, preserving skin integrity by lowering pro-inflammatory cytokines (IL-1α, TNF-α, IL-6, IL-8). It stimulates the TGF-β pathway, promoting collagen synthesis critical for skin firmness and elasticity, and inhibits matrix metalloproteinase 1 (MMP-1), an enzyme that degrades collagen and leads to wrinkle formation. The compound also modulates MAPK signaling involved in cellular stress responses and skin aging. Collectively, these mechanisms prevent wrinkle formation, increase skin elasticity, reduce redness, brighten skin, and support overall skin health, repair, and regeneration. (추천 피부타입: 모든피부타입)
関連文献
- Astaxanthin Function as Colour Source in Ornamental Fish · 2025
- Heterologous Expression of the Plant-Derived Astaxanthin Biosynthesis Pathway in Yarrowia lipolytica for Glycosylated Astaxanthin Production. · 2023
- Benefits of Carotenoid Astaxanthin: A Review · 2022
- Astaxanthin from bacteria as a feed supplement for animals · 2021
- Effect of astaxanthin on cutaneous wound healing · 2017